AI for amyloid drug discovery

Designing precision binders for amyloid diseases

We design novel biologics with AI and validate them in our own lab, focusing on the hardest unsolved problems in amyloid biology.

Partner with usView our pipeline
45M+people affected by amyloid diseases globally, including Alzheimer’s, Parkinson’s, ATTR and AL/AA amyloidosis
Our mission

Bring precision therapies for amyloid diseases to patients faster.

We design and validate binders that recognize the specific amyloid structures behind each disease. We advance them as therapeutics and diagnostics, in-house and with pharma and biotech partners.

Scientist at a fluorescence microscope workstation
Our technology

Generative AI paired with an accelerated lab.

We design binders in silico, then produce and test them in short cycles, selecting for polymorph specificity rather than pan-amyloid binding.

How it works
Tau fibril
Alzheimer’s
Tau FIA
Alzheimer’s
α-synuclein
Parkinson’s
TTR
Cardiomyopathy
DiscoveryLead OpCandidate selectionIND
Pipeline

Four programs across Alzheimer’s, Parkinson’s and ATTR.

Our tau fibril program is in candidate selection with UC Santa Barbara, alongside tau FIA in lead optimization and discovery programs for α-synuclein and TTR.

View our pipeline
Our software

The design platform we use, available to researchers.

De novo antibody design, 3D structure visualization and project management in the browser, with private enterprise deployments.

Explore the platform
Erica Keane RiveraSam LoboDevon CallanVentura Rivera
About us

Computational design and wet-lab validation under one roof.

A Santa Barbara team combining computational biophysics with wet-lab automation and antibody translation.

Meet the team

Get in touch with us

Have a difficult amyloid target, or interested in licensing one of our programs? We want to hear about it.

Connect with us
2435 Elings Hall, Santa Barbara, CA 93106
+1 (805) 714-9560